[ABSTRACT] The classic antiepileptics, as well as those recently introduced in therapeutics, present properties that allow their use in non-seizure disorders. Among these indications stand out their efficacy in the bipolar disorder, being an interesting alternative to lithium in some circumstances. So, carbamazepine is considered as a good alternative for the treatment of mania, with an efficacy similar to lithium and superior to placebo. However, in bipolar patients maintenance phases and in de