[ABSTRACT] Recently, different groups of experts and consensus groups have published guidelines on the psychopharmacological treatment of postraumatic stress disorder. Based on these guidelines, we will provide clinicians with the basic psychopharmacological treatment approaches. Furthermore, we will provide norms for the treatment of specif problems, such as, sleep disorders, aggression, and comorbidity. Finally, we will show in tabular form the open studies and clinical trials made with the di